• Product NamePBTZ169
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityPBTZ169 is a new drug candicate that inhibits decaprenylphosphoryl-β-d-ribose 2-oxidase (DprE1), more efficiently than BTZ043
• Target NameDprE1 inhibitor
• CAS No. 1377239-83-2
• Calculated MW 456.48
• Formulation C20H23F3N4O3S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Respiratory system/ Immunology system
  SMILES:C1CCC(CC1)CN2CCN(CC2)C3=NC(=O)C4=CC(=CC(=C4S3)[N+](=O)[O-])C(F)(F)F
  Pathways:Others
  Receptor:DprE1
  Boling pt:
  Melting pt:
  Solubility:DMSO: 6.4 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Gonzlez-Martnez NA,et al. In Vivo Activity of the Benzothiazinones PBTZ169 and BTZ043 against Nocardia brasiliensis. PLoS Negl Trop Dis. 2015 Oct 16;9(10):e0004022.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting