• Product NameCompound 4
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityNOD-IN-1 is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors, NOD1 and NOD2, with IC50 of 5.74 μM and 6.45 μM, respectively.
• Target NameNOD inhibitor
• CAS No. 132819-92-2
• Calculated MW 343.4
• Formulation C18H17NO4S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:O=C(C(N1S(=O)(C2=CC=C(C)C=C2)=O)=CC3=C1C=CC=C3)OCC
  Pathways:NF-κb
  Receptor:NOD1; NOD2
  Boling pt:
  Melting pt:
  Solubility:DMSO:10 mM
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. K, et al. Identification of indole scaffold-based dual inhibitors of NOD1 and NOD2. Bioorg Med Chem. 2016 Nov 1;24(21):5221-5234.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting