• Product NameNSC23005
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityNSC23005 sodium is a p18INK inhibitor. NSC23005 sodium Potently promotes hematopoietic stem cell (HSC) expansion (ED50 = 5.21 nM).
• Target NameCDK inhibitor
• CAS No. 6314-70-1
• Calculated MW 305.3238
• Formulation C13H16NNaO4S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:O=C([O-])C1=CC=C(S(=O)(NC2CCCCC2)=O)C=C1.[Na+]
  Pathways:Cell Cycle/Checkpoint
  Receptor:P18INK
  Boling pt:
  Melting pt:
  Solubility:Soluble in DMSO
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Xie XQ, et,al. Discovery of novel INK4C small-molecule inhibitors to promote human and murine hematopoietic stem cell ex vivo expansion. Sci Rep. 2015 Dec 18;5:18115.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting