• Product NameJNK-IN-7
• Brief DescriptionInhibitors
• Purification99.53%
• Biological ActivityJNK-IN-7 is a selective JNK inhibitor with IC50 values of 1.54 nM, 1.99 nM, 0.75 nM to JNK1, JNK2, JNK3, respectively. It also inhibits phosphorylation of c-Jun, which is a direct substrate of JNK kinase.
• Target NameJNK inhibitor
• CAS No. 1408064-71-0
• Calculated MW 493.56
• Formulation C28H27N7O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:CN(C)C/C=C/C(=O)NC1=CC=CC(=C1)C(=O)NC2=CC=C(C=C2)NC3=NC=CC(=N3)C4=CN=CC=C4
  Pathways:MAPK
  Receptor:JNK1; JNK2; JNK3
  Boling pt:
  Melting pt:
  Solubility:DMSO: >24.7mg/Ml
  Appearance:Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Zhang T, et al. Chem Biol, 2012, 19(1): 140-154.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting