• Product NameSolcitinib
• Brief DescriptionInhibitors
• Purification99.82%
• Biological ActivitySolcitinib, also known as GSK2586184 or GLPG0778, is a Janus kinase 1 (JAK1) inhibitor. Solcitinib may be potential useful for treatment of psoriasissystemic lupus erythematosus, ulcerative colitis.
• Target NameJAK inhibitor
• CAS No. 1206163-45-2
• Calculated MW 389.18
• Formulation C22H23N5O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:O=C(C1CC1)NC2=NN3C(C4=CC=C(C(N5CC(C)(C)C5)=O)C=C4)=CC=CC3=N2
  Pathways:Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
  Receptor:JAK1
  Boling pt:
  Melting pt:
  Solubility:DMSO: 20 mg/Ml
  Appearance:White powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Kahl L, et al. Lupus. 2016 Apr 6. pii: 0961203316640910.;

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting