• Product NameCP-640186 hydrochloride
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityCP-640186 Hcl is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively; with improved metabolic stability vs CP-610431.
• Target NameAcetyl-CoA Carboxylase inhibitor
• CAS No. 591778-70-0
• Calculated MW 522.08
• Formulation C30H35ClN3O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:C1C[C@H](CN(C1)C2CCN(CC2)C(=O)C3=C4C=CC=CC4=CC5=CC=CC=C53)C(=O)N6CCOCC6.Cl
  Pathways:Proteases/Proteasome
  Receptor:ACC1; ACC2
  Boling pt:
  Melting pt:
  Solubility:DMSO: 48 mg/Ml
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Harwood HJ Jr, et al. J Biol Chem. 2003 Sep 26;278(39):37099-111.;

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting