• Product NameMadrasin
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityMadrasin is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly. Madrasin stalls spliceosome assembly at the A complex.
• Target NameOthers inhibitor
• CAS No. 374913-63-0
• Calculated MW 311.34
• Formulation C16H17N5O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:O=C1NC(NC2=NC(C)=C3C=CC(OC)=CC3=N2)=NC(C)=C1C
  Pathways:Others
  Receptor:Others
  Boling pt:
  Melting pt:
  Solubility:Soluble in DMSO
  Appearance:Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Andrea Pawellek et al. J Biol Chem, 2014 Dec 12, 289(50): 34683-34698.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting