• Product NameIQ-1
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityMaintains embryonic stem cell (ESC) pluripotency in Wnt3a-treated cells; enables Wnt/β-catenin-driven expansion of mouse ESCs and prevents spontaneous differentiation. Upregulates expression of?Oct4?and?Sox2?transcription factors. Binds to serine/threonine phosphatase PP2A and prevents PP2A/Nkd interaction.
• Target NameOthers
• CAS No. 331001-62-8
• Calculated MW 362.42
• Formulation C21H22N4O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:CC(=O)C1=CC=C(C=C1)N/N=C(\C2=NC(CC3=CC=CC=C32)(C)C)/C(=O)N
  Pathways:Others
  Receptor:Others
  Boling pt:
  Melting pt:
  Solubility:DMSO: 33 mg/mL
  Appearance:Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Miyabayashi T, et al. Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5668-73.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting