• Product NameA-804598
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityA-804598 is a novel, competitive, and selective P2X7 receptor antagonist with IC50 of 10 nM, 9 nM and 11 nM in rat, mouse and human P2X7 receptors respectively.
• Target NameP2 Receptor antagonist
• CAS No. 1125758-85-1
• Calculated MW 315.37
• Formulation C19H17N5
• Storage -20°C for 3 years | In solvent: -80°C for 1 year

• Research Area:Others
  SMILES:C[C@@H](C1=CC=CC=C1)N=C(NC#N)NC2=CC=CC3=C2C=CC=N3
  Pathways:Neuroscience
  Receptor:P2X7
  Boling pt:
  Melting pt:
  Solubility:DMSO: 32 mg/mL
  Appearance:Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Donnelly-Roberts DL, et al. Neuropharmacology. 2009 Jan;56(1):223-9.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting