• Product NameBAW2881
• Brief DescriptionInhibitors
• Purification99.97%
• Biological ActivityBAW2881 is a potent and selective VEGFR inhibitor (vascular endothelial growth factor receptor tyrosine kinase inhibitor) with activity to inhibit chronic and acute skin inflammation.
• Target NameBcr-Abl inhibitor; Raf inhibitor; VEGFR inhibitor
• CAS No. 861875-60-7
• Calculated MW 424.38
• Formulation C22H15F3N4O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:O=C(C1=C2C=CC(OC3=NC(N)=NC=C3)=CC2=CC=C1)NC4=CC=CC(C(F)(F)F)=C4
  Pathways:Angiogenesis; MAPK; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
  Receptor:c-Abl; B-Raf (V599E); C-Raf-1; hVEGFR2
  Boling pt:
  Melting pt:
  Solubility:DMSO: 33 mg/mL
  Appearance:Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Halin C, et al. Am J Pathol. 2008 Jul;173(1):265-77.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting