• Product NameSTO-609 acetate
• Brief DescriptionInhibitors
• Purification99.75%
• Biological ActivitySelective, cell-permeable inhibitor of Ca2+-calmodulin-dependent protein kinase kinase (Ki?values are 80 and 15 ng/ml for inhibition of CaM-KKα?and CaM-KKβ?respectively); competes for the ATP-binding site. Displays > 80-fold selectivity over CaMK1, CaMK2, CaMK4, MLCK, PKC, PKA and p42 MAPK.
• Target NameCaMK inhibitor
• CAS No. 1173022-21-3
• Calculated MW 374.35
• Formulation C19H10N2O3C2H4O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:CC(=O)O.C1=CC=C2C(=C1)N=C3N2C(=O)C4=CC=CC5=C(C=CC3=C54)C(=O)O
  Pathways:Neuroscience
  Receptor:CaM-KKα; CaM-KKβ
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mM (with sonication)
  Appearance:Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Tokumitsu H, et al. J Biol Chem. 2002 May 3;277(18):15813-8.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting