• Product NameSesamol?
• Brief DescriptionInhibitors
• Purification99.90%
• Biological ActivitySesamol could decrease lung inflammation and lipopolysaccharide (LPS)-induced lung injury in rats. Sesamol ameliorates inflammatory and oxidative damage by upregulating AMPK activation and Nrf2 signaling and blocking the NF-κB and MAPK signaling pathways and inhibits melanin biosynthesis by down-regulating tyrosinase activity and melanin production via regulation of gene expression of melanogenesis-related proteins through modulation of MITF activity, which promotes phosphorylation of p38 and JNK in melan-a cells.
• Target NameAMPK activator
• CAS No. 533-31-3
• Calculated MW 138.12
• Formulation C7H6O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:C1OC2=C(O1)C=C(C=C2)O
  Pathways:PI3K/Akt/mTOR signaling
  Receptor:AMPK
  Boling pt:
  Melting pt:
  Solubility:Chloroform, Dichloromethane, Ethyl Acetate, DMSO,?
  Appearance:Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Wu XL, et al. Inflamm Res. 2015 Aug;64(8):577-88.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting