• Product NameSR9011
• Brief DescriptionInhibitors
• Purification99.65%
• Biological ActivitySR9011 as an agonist of? REV-ERB with IC50 = 790 nM for REV-ERBα and IC50 = 560 nM for REV-ERBβ.
• Target NameAutophagy agonist
• CAS No. 1379686-29-9
• Calculated MW 479.04
• Formulation C23H31ClN4O3S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:CCCCCNC(=O)N1CCC(C1)CN(CC2=CC=C(C=C2)Cl)CC3=CC=C(S3)[N+](=O)[O-]
  Pathways:Autophagy
  Receptor:Rev-ErbBα; Rev-ErbBβ
  Boling pt:
  Melting pt:
  Solubility:DMSO: 43 mg/mL
  Appearance:Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Solt LA, et al. Nature. 2012 Mar 29;485(7396):62-8.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting