• Product NameBay 59-3074
• Brief DescriptionInhibitors
• Purification99.69%
• Biological ActivityBay 59-3074 is a novel CB1/CB2?receptor partial agonist (Ki?values are 48.3 and 45.5 nM at human CB1?and CB2?receptors respectively). Orally active CB1?agonist?in vivo. Displays anti-hyperalgesic and antiallodynic properties in rat models of chronic neuropathic and inflammatory pain.
• Target NameCannabinoid Receptor agonist
• CAS No. 406205-74-1
• Calculated MW 420.44?
• Formulation C21H21FN8O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:O=S(CCCC(F)(F)F)(OC1=CC=CC(OC2=CC=CC(C(F)(F)F)=C2C#N)=C1)=O
  Pathways:GPCR/G Protein
  Receptor:CB1; CB2
  Boling pt:
  Melting pt:
  Solubility:DMSO: 34 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. De Vry J, et al. J Pharmacol Exp Ther. 2004 Aug;310(2):620-32.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting