• Product NameXMD8-87
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityXMD8-87 is a TNK2 inhibitor. XMD8-87 showed activity in the inhibition of TNK2 phosphorylation. XMD8-87 and XMD16-5 potently inhibit phosphorylation of TNK2 truncation mutations found in solid tumor types.
• Target NamePPAR inhibitor
• CAS No. 1234480-46-6
• Calculated MW 445.22
• Formulation C24H27N7O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:C1=NC(NC2=CC=C(N3CCN(C)CC3)C=C2OC)=NC2N(C)C3C=CC=CC=3C(=O)NC1=2
  Pathways:Metabolism
  Receptor:TNK2; TNK2
  Boling pt:
  Melting pt:
  Solubility:DMSO:65 mg/mL (145.89 mM); Ethanol: 10 mg/mL (22.44 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Maxson JE, et al. Y Res. 2016, 76(1):127-38.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting