• Product NameBAY-876
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityBAY-876 is a potent and Selective GLUT1 Inhibitor. BAY-876 showed good metabolic stability in?vitro and high oral bioavailability in?vivo. GLUT1 overexpression has been reported in many types of human Ys, including those of brain,6 breast, colon, kidney, lung, ovary, and prostate, and is correlated with advanced Y stages and poor clinical outcomes.
• Target Nametransporter inhibitor
• CAS No. 1799753-84-6
• Calculated MW 496.12
• Formulation C24H16F4N6O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:O=C(C1=NC2=CC(F)=CC=C2C(C(NC3=C(C)N(CC4=CC=C(C=C4)C#N)N=C3C(F)(F)F)=O)=C1)N
  Pathways:Metabolism
  Receptor:GLUT1; GLUT2; GLUT3; GLUT4
  Boling pt:
  Melting pt:
  Solubility:DMSO: 29 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Siebeneicher H et al. ChemMedChem. 2016 Aug 23.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting