• Product NameSUN 11602
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivitySUN11602 is a novel aniline compound, which mimics the neuroprotective mechanisms of basic fibroblast growth factor. Basic fibroblast growth factor (bFGF) mimetic. Mimics the neuroprotective effects of bFGF; prevents glutamate-induced neuronal death. Increases levels of CALB1 gene expression in cerebrocortical neurons. Triggers phosphorylation of FGFR, ERK1 and ERK2.
• Target NameERK activator; FGFR activator
• CAS No. 704869-38-5
• Calculated MW 451.61
• Formulation C26H37N5O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:O=C(N)C1=CC=C(CN2CCC(N(C)C(CNC3=C(C)C(C)=C(N)C(C)=C3C)=O)CC2)C=C1
  Pathways:Angiogenesis; MAPK; Tyrosine Kinase/Adaptors
  Receptor:ERK1; ERK2; FGFR
  Boling pt:
  Melting pt:
  Solubility:DMSO: 50 Mm; Ethanol: 20 mM
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Murayama, et al. ACS Chem.Neurosci. 4 266.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting