• Product NameMethyl protodioscin
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityMethyl protodioscin has antitumor property. Methyl protodioscin potentially increase HDL cholesterol while reducing LDL cholesterol and triglycerides.Methyl protodioscin induced apoptotic process in human A549 cells is closely associated with Mitochondrial membrane potential, mitochondrial cytochrome c and caspase-3
• Target NameApoptosis inducer inhibitor
• CAS No. 54522-52-0
• Calculated MW 1063.23
• Formulation C52H86O22
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:C[C@H]1[C@H]2[C@H](C[C@@H]3[C@@]2(CC[C@H]4[C@H]3CC=C5[C@@]4(CC[C@@H](C5)O[C@H]6C([C@H]([C@@H]([C@H](O6)CO)O[C@H]7[C@@H]([C@@H]([C@H]([C@@H](O7)C)O)O)O)O)O[C@H]8[C@@H]([C@@H]([C@H]([C@@H](O8)C)O)O)O)C)C)O[C@@]1(CC[C@@H](C)CO[C@H]9[C@@H]([C@H]([C@@H]([C@H](O9)CO)O)O)O)OC
  Pathways:Apoptosis
  Receptor:Apoptosis inducer
  Boling pt:
  Melting pt:
  Solubility:Soluble in Pyridine, Methanol, Ethanol
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Ma W,et al.Methyl protodioscin increases ABCA1 expression and cholesterol efflux while inhibiting gene expressions for synthesis of cholesterol and triglycerides by suppressing SREBP transcription and microRNA 33a/b levels.Atherosclerosis. 2015 Apr;239(2):566-70.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting