• Product Name(20S)-20-(β-D-Glucopyranosyloxy)dammara-24-ene-3β,12β-diol
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityGinsenoside compound K (C-K) could be a potentially effective anti-colorectal cancer agent. C-K showed significant anti-proliferative effects in HCT-116 and SW-480 cells at concentrations of 30-50 ?M.C-K could be a potential drug for pediatric AML intervention and to improve the outcome of pediatric AML treatment, via significant G1 cell cycle arrest and apoptosis. C-K reduced the expression levels of the inducible NO synthase (iNOS) and COX-2 proteins and inhibited the activation of NF-kB, a nuclear transcription factor. 5. Ginsenoside Rb1 can be transformed to CK by intestinal bacteria, and C-K may be effective against inflammation.
• Target Namecell cycle arrest inhibitor
• CAS No. 39262-14-1
• Calculated MW 622.884
• Formulation C36H62O8
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:CC(=CCC[C@@](C)([C@H]1CC[C@@]2([C@@H]1[C@@H](C[C@H]3[C@]2(CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)C)O)C)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O)C
  Pathways:Cell Cycle/Checkpoint
  Receptor:cell cycle arrest
  Boling pt:
  Melting pt:
  Solubility:Soluble in Pyridine, Methanol, Ethanol
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Yang XD,et al. A review of biotransformation and pharmacology of ginsenoside compound K. Fitoterapia. 2015 Jan;100:208-20.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting