• Product NameBavachin
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityBavachin is a weak antioxidant. Bavachin acts as a weak phytoestrogen by binding and activating the estrogen receptor. Bavachin stimulates bone formation and has potential activity against osteoporosis. Bavachin has antimutagenic effect, shows inhibitory activities against the antigen-induced degranulation. Bavachin has anti-inflammation effect, can protect cartilage from inflammation-mediated damage in joints of osteoarthritis patients, through decreasing IL-1 beta-induced activation of IKK-I kappaB alpha-NF-kappaB signaling pathway .
• Target NameEstrogen/progestogen Receptor activator
• CAS No. 19879-32-4
• Calculated MW 324.376
• Formulation C20H20O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:CC(=CCC1=C(C=C2C(=C1)C(=O)C[C@H](O2)C3=CC=C(C=C3)O)O)C
  Pathways:Endocrinology/Hormones
  Receptor:ERα; ERβ
  Boling pt:
  Melting pt:
  Solubility:Soluble in Chloroform, Dichloromethane, Ethyl Acetate, DMSO
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Park J1,et al. Activation of Estrogen Receptor by Bavachin from Psoralea corylifolia. Biomol Ther (Seoul). 2012 Mar;20(2):183-8.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting