• Product Namemagnolin
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityMagnolin has anti-inflammatory and antioxidative effects. Magnolin reduces the renal oxidative stress, suppresses caspase-3 activity, and increases Bcl-2 expression in vivo and in vitro. Magnolin might be a naturally occurring chemoprevention and therapeutic agent capable of inhibiting cell proliferation and transformation by targeting c.
• Target NameERK inhibitor
• CAS No. 31008-18-1
• Calculated MW 416.47
• Formulation C23H28O7
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:COC1=C(C=C(C=C1)[C@@H]2[C@H]3CO[C@@H]([C@H]3CO2)C4=CC(=C(C(=C4)OC)OC)OC)OC
  Pathways:MAPK
  Receptor:ERK1; ERK2
  Boling pt:
  Melting pt:
  Solubility:Soluble in Chloroform, Dichloromethane, Ethyl Acetate, DMSO
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Wang F,et al. Magnolin protects against contrast-induced nephropathy in rats via antioxidation and antiapoptosis. Oxid Med Cell Longev. 2014;2014:203458.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting