• Product NameAlpinetin
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityAlpinetin has antibacterial activity. Alpinetin has anti-inflammatory activity. Alpinetin can enhance the sensitivity of HepG2 hepatoma cells to the chemotherapeutic agent CDDP. Alpinetin has strong anti-hepatoma and pancreatic cancer cells effects, by inhibiting proliferation ,regulating of the Bcl-2 family and XIAP expression, releasing of cytochrome c and activating caspases.
• Target NameBcr-Abl inhibitor
• CAS No. 36052-37-6
• Calculated MW 270.284
• Formulation C16H14O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:COC1=C2C(=O)C[C@H](OC2=CC(=C1)O)C3=CC=CC=C3
  Pathways:Angiogenesis; Cytoskeletal Signaling
  Receptor:Bcl-2
  Boling pt:
  Melting pt:
  Solubility:Soluble in Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Guan S,et al. Immunosuppressive activity of alpinetin on activation and cytokines secretion of murine T lymphocytes. Immunopharmacol Immunotoxicol. 2014 Aug;36(4):290-6.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting