• Product NameLoureirin B
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityLoureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress TGF-β1-induced fibrosis, during which TGF-β1/Smad2/3 pathway is likely involved.
• Target NameOthers inhibitor
• CAS No. 119425-90-0
• Calculated MW 316.353
• Formulation C18H20O5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism/Nervous system
  SMILES:COC1=CC(=C(C(=C1)OC)CCC(=O)C2=CC=C(C=C2)O)OC
  Pathways:Others
  Receptor:Others
  Boling pt:
  Melting pt:
  Solubility:Soluble in DMSO
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Bai X, et al. Loureirin B inhibits fibroblast proliferation and extracellular matrix deposition in hypertrophic scar via TGF-β/Smad pathway. Exp Dermatol. 2015 May;24(5):355-60.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting