• Product NameNeoandrographolide
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityNeoandrographolide has potent hypolipidemic effect and protects the cardiovascular without significant liver damage. Neoandrographolide has anti-inflammatory effect, might result from inhibition of iNOS and COX-2 expression through inhibiting p38 MAPKs activation. Neoandrographolide as chemosensitizer in S-Jurkat and X chromosome-linked inhibitor of apoptosis protein (XIAP)-overexpressing Jurkat cells, a model for chemoresistance.
• Target NameCOX inhibitor; NOS inhibitor
• CAS No. 27215-14-1
• Calculated MW 480.598
• Formulation C26H40O8
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:C[C@]1(CCC[C@@]2([C@@H]1CCC(=C)[C@H]2CCC3=CCOC3=O)C)CO[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O
  Pathways:Immunology/Inflammation; Neuroscience
  Receptor:COX-2; iNOS
  Boling pt:
  Melting pt:
  Solubility:Soluble in Pyridine, Methanol, Ethanol
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Yang T,et al. Hypolipidemic effects of andrographolide and neoandrographolide in mice and rats. Phytother Res. 2013 Apr;27(4):618-23.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting