• Product NameSaikosaponin D
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivitySaikosaponin is a novel SERCA inhibitor by inhibiting NF-κB and STAT3 signaling to protect against acetaminophen-induced hepatotoxicity.
• Target NameNF-κB inhibitor; STAT inhibitor
• CAS No. 20874-52-6
• Calculated MW 780.98
• Formulation C42H68O13
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:C[C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)O[C@H]2CC[C@]3([C@H]([C@]2(C)CO)CC[C@@]4([C@@H]3C=C[C@@]56[C@]4(C[C@H]([C@@]7([C@H]5CC(CC7)(C)C)CO6)O)C)C)C)O)O[C@H]8[C@@H]([C@H]([C@@H]([C@H](O8)CO)O)O)O)O
  Pathways:JAK/STAT signaling; NF-κb; Stem Cells
  Receptor:NF-κB; STAT3
  Boling pt:
  Melting pt:
  Solubility:Pyridine, Methanol, Ethanol, etc.
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Liu RY1, Li JP.Saikosaponin-d inhibits proliferation of human undifferentiated thyroid carcinoma cells through induction of apoptosis and cell cycle arrest.Eur Rev Med Pharmacol Sci. 2014;18(17):2435-43.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting