• Product NameSaikosaponin C
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivitySaikosaponin C efficiently inhibited LPS-induced apoptotic cell death via inhibition of caspase-3 activation and caspase-3-mediated-FAK degradation.
• Target NameCaspase inhibitor
• CAS No. 20736-08-7
• Calculated MW 927.14
• Formulation C48H72O17
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:O[C@@H]1[C@H]2[C@](C(OC3)C(C)(C)C3C2)([H])[C@H]4[C@@]([C@@](CC[C@]5([H])[C@]6(C)CC[C@H](O[C@H]7[C@H](O)[C@@H](O)[C@H](O[C@H]8O[C@@H](C)[C@H](O)[C@@H](O)[C@H]8O)[C@@H](CO[C@H]9[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O9)O7)C5(C)C)(C)[C@]6([H])C=C4)(C)C1
  Pathways:Apoptosis; Proteases/Proteasome
  Receptor:Caspase-3
  Boling pt:
  Melting pt:
  Solubility:Pyridine, Methanol, Ethanol, etc.
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Lee TH1, Chang J2, Kim BM3.Saikosaponin C inhibits lipopolysaccharide-induced apoptosis by suppressing caspase-3 activation and subsequent degradation of focal adhesion kinase in human umbilical vein endothelial cells.Biochem Biophys Res Commun. 2014 Mar 14;445(3):615-21.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting