• Product NameJatrorrhizine
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityJatrorrhizine is a protoberberine alkaloid isolated from Enantia chlorantha (Annonaceae) and other species. It was found to have antimicrobial and antifungal activity. It binds and noncompetitively inhibits monoamine oxidase (IC50 4 micromolar for MAO-A and 62 for MAO-B).
• Target NameMAO inhibitor
• CAS No. 3621-38-3
• Calculated MW 338.382
• Formulation C20H20NO4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC(=C(C=C4CC3)O)OC)OC
  Pathways:Metabolism
  Receptor:MAO-A; MAO-B
  Boling pt:
  Melting pt:
  Solubility:Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Wu H1, He K2, Wang Y2, et al.The antihypercholesterolemic effect of jatrorrhizine isolated from Rhizoma Coptidis.Phytomedicine. 2014 Sep 25;21(11):1373-81.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting