• Product NameICA069673
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityICA-069673 is a KCNQ2/Q3 potassium channel activator with an IC50 of 0.69 μM.
• Target NamePotassium Channel activator
• CAS No. 582323-16-8
• Calculated MW 269.63
• Formulation C11H6CLF2NO3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:C1=CC(=C(C=C1C(=O)NC2=CN=C(N=C2)Cl)F)F
  Pathways:Membrane transporter/Ion channel
  Receptor:KCNQ2/Q3 potassium channel
  Boling pt:
  Melting pt:
  Solubility:DMSO: 34mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Wickenden AD, et al. N-(6-chloro-pyridin-3-yl)-3,4-difluoro-benzamide (ICA-27243): a novel, selective KCNQ2/Q3 potassium channel activator. Mol Pharmacol. 2008 Mar;73(3):977-86. Epub 2007 Dec 18.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting