• Product NameCYM 5541
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityCYM-5541 (ML249) is an selective and allosteric S1P3 receptor agonist with an EC50 between 72 and 132 nM.
• Target NameS1P Receptor inhibitor
• CAS No. 945128-26-7
• Calculated MW 316.44
• Formulation C19H28N2O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:C1CCC(CC1)N(C2CCCCC2)C(=O)C3=NOC(=C3)C4CC4
  Pathways:GPCR/G Protein
  Receptor:S1P3
  Boling pt:
  Melting pt:
  Solubility:DMSO: 39 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Jo E, et al. Novel selective allosteric and bitopic ligands for the S1P(3) receptor. ACS Chem Biol. 2012 Dec 21;7(12):1975-83.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting