• Product NameTPI-1
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityTPI-1 is a SHP-1 inhibitor;? inhibits recombinant SHP-1 with an IC50 of 40 nM.
• Target NameGlucocorticoid Receptor inhibitor
• CAS No. 79756-69-7
• Calculated MW 253.078
• Formulation C12H6Cl2O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:C1=CC(=C(C=C1Cl)C2=CC(=O)C=CC2=O)Cl
  Pathways:Endocrinology/Hormones
  Receptor:recombinant SHP-1
  Boling pt:
  Melting pt:
  Solubility:DMSO:10 mM
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Kundu S, et al. Novel SHP-1 inhibitors tyrosine phosphatase inhibitor-1 and analogs with preclinical anti-tumor activities as tolerated oral agents. J Immunol. 2010 Jun 1;184(11):6529-36.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting