• Product NameVUF10460
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityVUF10460 is a non-imidazole histamine H4 receptor agonist; binds to rat H4 receptor with a pKi of 7.46.
• Target NameHistamine Receptor inhibitor
• CAS No. 1028327-66-3
• Calculated MW 269.352
• Formulation C15H19N5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:CN1CCN(CC1)C2=NC(=NC(=C2)C3=CC=CC=C3)N
  Pathways:GPCR/G Protein; Immunology/Inflammation; Neuroscience
  Receptor:H4 receptor
  Boling pt:
  Melting pt:
  Solubility:DMSO: 36 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Coruzzi G, et al. Selective histamine H? and H? receptor agonists exert opposite effects against the gastric lesions induced by HCl in the rat stomach. Eur J Pharmacol. 2011 Nov 1;669(1-3):121-7.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting