• Product NameCasin
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityNapabucasin is an orally available Stat3 and cancer cell stemness inhibitor.
• Target NameSTAT inhibitor
• CAS No. 425399-05-9
• Calculated MW 306.409
• Formulation C20H22N2O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:C1CC(C2=C(C1)C3=C(N2)C=CC(=C3)C4=CC=CC=C4)NCCO
  Pathways:JAK/STAT signaling; Stem Cells
  Receptor:STAT3
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Li Y,et al. Suppression of cancer relapse and metastasis by inhibiting cancer stemness. Proc Natl Acad Sci U S A. 2015 Feb 10;112(6):1839-44.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting