• Product NameAcacetin
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityAcacetin has anti-plasmodial activity and anti-peroxidant activity. Also acacetin is an ATP-competitive PI3-K inhibitor. And has anti-cancer and antitumor activities, such as prostate cancer, melanoma angiogenesis tumor , via Akt/NF-κB,Stat signaling pathway.Has anti-inflammatory and antiarthritic effects in FLSs, can inhibit p38 and JNK phosphorylation and reduces MMP-1, MMP-3 and MMP-13 expression in interleukin-1β-induced FLSs.
• Target NameCOX inhibitor; IAP inhibitor
• CAS No. 480-44-4
• Calculated MW 284.3
• Formulation C16H12O5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:OC1=CC(O)=C(C(C=C(C2=CC=C(OC)C=C2)O3)=O)C3=C1
  Pathways:Immunology/Inflammation; Apoptosis; Neuroscience
  Receptor:COX-2; XIAP
  Boling pt:
  Melting pt:
  Solubility:DMSO: >10.7mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Zieliska, S. and Matkowski, A. Phytochemistry and bioactivity of aromatic and medicinal plants from the genus Agastache (Lamiaceae). Phytochem. Rev. 13(2), 391-416 (2014).

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting