• Product NameTOFA (RMI14514;MDL14514)
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityTOFA (RMI14514;MDL14514) is an allosteric inhibitor of acetyl-CoA carboxylase-α (ACCA ).
• Target NameAcetyl-CoA Carboxylase inhibitor
• CAS No. 54857-86-2
• Calculated MW 324.45
• Formulation C19H32O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:CCCCCCCCCCCCCCOC1=CC=C(O1)C(=O)O
  Pathways:Proteases/Proteasome
  Receptor:ACC1
  Boling pt:
  Melting pt:
  Solubility:DMSO: 34 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Wang C., et al. Acetyl-CoA carboxylase-alpha inhibitor TOFA induces human cancer cell apoptosis. Biochem Biophys Res Commun. 2009 Jul 31;385(3):302-6.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting