• Product NameAN2718
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityAN2718 is a benzoxaborole compound that displays broad antifungal effectiveness in vitro. It inhibits leucyl-tRN/A synthetase (LeuRS) from molds and yeasts (IC50s = 2 and 4.2 ?M for A. fumigatus and C. albicans LeuRS, respectively), blocking protein synthesis.
• Target NameOthers inhibitor
• CAS No. 174672-06-1
• Calculated MW 168.4
• Formulation C7H6BClO2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:ClC1=CC=C(B(O)OC2)C2=C1
  Pathways:Others
  Receptor:leucyl-tRN/A synthetase
  Boling pt:
  Melting pt:
  Solubility:Soluble in DMSO
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Aditya K Gupta., et al. InvestigatioN/Al drugs for onychomycosis. Expert Opin Investig Drugs. 2014 Jan;23(1):97-106.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting