• Product NameTalabostat mesylate
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityTalabostat mesylate is an orally active, specific inhibitor of dipeptidyl peptidases with IC50 of 1 nM for DPP4, including tumor-associated fibroblast activation protein.
• Target NameDPP-4 inhibitor
• CAS No. 150080-09-4
• Calculated MW 310.18
• Formulation C10H23BN2O6S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:B([C@@H]1CCCN1C(=O)[C@H](C(C)C)N)(O)O.CS(=O)(=O)O
  Pathways:Proteases/Proteasome
  Receptor:DPP-4
  Boling pt:
  Melting pt:
  Solubility:DMSO: 40 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Cristillo AD, et al. HIV-1 Env vaccine comprised of electroporated DNA and protein co-administered with Talabostat. Biochem Biophys Res Commun. 2008 May 23;370(1):22-6.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting