• Product NameMonastrol
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityMonastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5 with an IC50 value of 14 μM.
• Target NameKinesin inhibitor
• CAS No. 329689-23-8
• Calculated MW 292.35
• Formulation C14H16N2O3S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:CCOC(=O)C1=C(NC(=S)NC1C2=CC(=CC=C2)O)C
  Pathways:Cytoskeletal Signaling
  Receptor:Eg5
  Boling pt:
  Melting pt:
  Solubility:DMSO: 33 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Cochran JC, et al. Monastrol inhibition of the mitotic kinesin Eg5. J BiolChem. 2005 Apr 1;280(13):12658-67.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting