• Product Namely2334737
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityLY2334737 is an orally available prodrug of gemcitabine which is a nucleoside analog used as chemotherapy
• Target NameOthers
• CAS No. 892128-60-8
• Calculated MW 389.39
• Formulation C17H25F2N3O5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CCCC(CCC)C(=O)NC1=NC(=O)N(C=C1)[C@H]2C([C@@H]([C@H](O2)CO)O)(F)F
  Pathways:Others
  Receptor:Others
  Boling pt:
  Melting pt:
  Solubility:10 mM in DMSO
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Pratt SE, et al. Human carboxylesterase-2 hydrolyzes the prodrug of gemcitabine (LY2334737) and confers prodrug sensitivity to cancer cells. Clin Cancer Res. 2013 Mar 1;19(5):1159-68.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting