• Product NameZINC00881524
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityZINC00881524 is a potent and selective ROCK inhibitor. Clinically, inhibition of ROCK pathway is believed to contribute to some of the cardiovascular benefits of statin therapy that are independent of lipid lowering (ie, pleiotropic effects).
• Target NameROCK inhibitor
• CAS No. 557782-81-7
• Calculated MW 380.462
• Formulation C21H20N2O3S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:CC12C(C(C3=CC=CC=C3O1)NC(=S)N2C4=CC=CC=C4)C(=O)OCC=C
  Pathways:Cell Cycle/Checkpoint; Stem Cells
  Receptor:ROCK
  Boling pt:
  Melting pt:
  Solubility: 300 mg/mL in DMSO
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

NCBI

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting