• Product NameVardenafil hydrochloride trihydrate
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityVardenafil HCl Trihydrate is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively.
• Target NamePDE inhibitor; PED inhibitor
• CAS No. 330808-88-3
• Calculated MW 579.11
• Formulation C23H32N6O4SHCl3H
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Endocrine system
  SMILES:CCCC1=NC(=C2N1NC(=NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)CC)OCC)C.O.O.O.Cl
  Pathways:Metabolism
  Receptor:PDE1; PDE5
  Boling pt:
  Melting pt:
  Solubility:DMSO: 100mg/ml(172.68 mM);Water: 10mg/ml(17.27 mM);Ethanol: 20mg/ml(34.54 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1 Saenz de Tejada I, et al. Int J Impot Res, 2001, 13(5), 282-290.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting