• Product Name3-TYP
• Brief DescriptionInhibitors
• Purification98.00%
• Biological Activity3-TYP is a selective?SIRT3?inhibitor.
• Target NameSirtuin inhibitor
• CAS No. 120241-79-4
• Calculated MW 146.15
• Formulation C7H6N4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:C1=CC(=CN=C1)C2=NNN=C2
  Pathways:Chromatin/Epigenetic; DNA Damage/DNA Repair
  Receptor:SIRT1; SIRT2; SIRT3
  Boling pt:
  Melting pt:
  Solubility:DMSO: 29 mg/mL (198.42 mM) Ethanol: 29 mg/mL (198.42 mM) Water: 5 mg/mL (34.21 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Pi H, et al. SIRT3-SOD2-mROS-dependent autophagy in cadmium-induced hepatotoxicity and salvage by melatonin. Autophagy. 2015;11(7):1037-51

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting