• Product NameOTS514
• Brief DescriptionInhibitors
• Purification99.02%
• Biological ActivityOTS514 is a highly potent TOPK(T-LAK cell-originated protein kinase) inhibitor with an IC50 value of 2.6 nM.
• Target NameTOPK inhibitor
• CAS No. 1338540-63-8
• Calculated MW 364.463
• Formulation C21H20N2O2S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:others
  SMILES:CC1=CC(=C(C2=C1NC(=O)C3=C2C=CS3)C4=CC=C(C=C4)C(C)CN)O
  Pathways:MAPK
  Receptor:TOPK
  Boling pt:
  Melting pt:
  Solubility:DMSO:100 mg/mL (194.73 mM);Insoluble in ethanol;Insoluble in H2O
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Kato T, et al. Oncotarget. 2016, 7(14):17652-64.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting