• Product NameIRAK4-IN-1
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityIRAK4-IN-1 is an interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor with an IC50 of 7 nM.
• Target NameAntiviral inhibitor
• CAS No. 1820787-94-7
• Calculated MW 337.42
• Formulation C19H23N5O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:CC1=NC2=CC=CC=C2N1CCCNC3=NC(=O)C4=C(N3)CCCC4
  Pathways:Immunology/Inflammation
  Receptor:IRAK-4
  Boling pt:
  Melting pt:
  Solubility:Soluble in DMSO
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Smith GF, et al. Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation. Bioorg Med Chem Lett. 2017 Jun 15;27(12):2721-2726.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting