• Product NameDelpazolid
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityDelpazolid, also known as LCB01-0371, is a new oxazolidinone with cyclic amidrazone. In vitro activity of LCB01-0371 against 624 clinical isolates was evaluated and compared with those of linezolid, vancomycin, and other antibiotics. LCB01-0371 showed good activity against Gram-positive pathogens. In vivo activity of LCB01-0371 against systemic infections in mice was also evaluated. LCB01-0371 was more active than linezolid against these systemic infections. LCB01-0371 showed bacteriostatic activity against Staphylococcus aureus.
• Target NameOthers
• CAS No. 1219707-39-7
• Calculated MW 308.313
• Formulation C14H17FN4O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:O=C1O[C@@H](CO)CN1C2=CC=C(N3C=NN(C)CC3)C(F)=C2
  Pathways:Others
  Receptor:Others
  Boling pt:
  Melting pt:
  Solubility:Soluble in DMSO
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Jeong JW, et al. In vitro and in vivo activities of LCB01-0371, a new oxazolidinone.Antimicrob Agents Chemother. 2010 Dec;54(12):5359-62. Jeong JW1,

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting