• Product Namerac-BHFF
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityPotent and selective GABA B receptor positive allosteric modulator that increases the potency and efficacy of GABA ( > 15-fold and > 149% respectively). Exhibits anxiolytic activity in vivo and is orally active.
• Target NameGABA Receptor inhibitor
• CAS No. 123557-91-5
• Calculated MW 330.344
• Formulation C17H21F3O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:CC(C)(C)C1=CC(=C2C(=C1)C(C(=O)O2)(C(F)(F)F)O)C(C)(C)C
  Pathways:Membrane transporter/Ion channel; Neuroscience
  Receptor:GABAB
  Boling pt:
  Melting pt:
  Solubility:DMSO: 15mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Krishnamurthy S,et al. Crystal structure of (1R,4R)-tert-butyl 3-oxo-2-oxa-5-aza?bicyclo?[2.2.2]octane-5-carboxylate,Acta Crystallogr E Crystallogr Commun. 2015 Jul 1; 71(Pt 7): o449Co450.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting