• Product Namelavendustin B
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityLavendustin B is a Tyrosine Kinase Inhibitor and an inhibitor of HIV-1 integrase (IN) interaction with its cognate cellular cofactor, lens epithelium-derived growth factor (LEDGF/p75)
• Target NameTyrosine Kinaseinhibitor; HIV-1 integrase
• CAS No. 125697-91-8
• Calculated MW 365.385
• Formulation C21H19NO5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:O=C(O)C1=CC(N(CC2=CC=CC=C2O)CC3=CC=CC=C3O)=CC=C1O
  Pathways:Proteases/Proteasome
  Receptor:Tyrosine Kinase inhibitor; HIV-1 integrase
  Boling pt:
  Melting pt:
  Solubility:Soluble in DMSO
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Agharbaoui FE, et al. Computational and synthetic approaches for developing Lavendustin B derivatives as allosteric inhibitors of HIV-1 integrase. Eur J Med Chem. 2016 Nov 10;123:673-83

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting