• Product NameSDZ285-428
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityNVP-VID-400, also known as SDZ285-428, is CYP24A1 inhibitor.
• Target NameP450 inhibitor
• CAS No. 174262-13-6
• Calculated MW 401.894
• Formulation C24H20ClN3O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:O=C(C1=CC=C(C2=CC=C(Cl)C=C2)C=C1)NCC(N3C=CN=C3)C4=CC=CC=C4
  Pathways:Metabolism
  Receptor:CYP24A1
  Boling pt:
  Melting pt:
  Solubility:Soluble in DMSO
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Bruno RD1,et al. Targeting cytochrome P450 enzymes: a new approach in anti-cancer drug development.Bioorg Med Chem. 2007 Aug 1;15(15):5047-60.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting