• Product Namehnps-PLA Inhibitor
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityHnps-PLA Inhibitor, is an inhibitor of human nonpancreatic secretory Phospholipase A (hnps-PLA). The best one inhibited hnps-PLA(2) and LTA(4)H-h with IC(50) values of 9.2 0.5 μM and 2.4 1.4 μM, respectively
• Target NameLTR inhibitor; Phospholipase inhibitor
• CAS No. 185298-58-2
• Calculated MW 379.42
• Formulation C21H21N3O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:O=C(N)C(C1=C(CC)N(CC2=CC=CC=C2)C3=C1C(OCC(N)=O)=CC=C3)=O
  Pathways:Immunology/Inflammation; Metabolism
  Receptor:LTA(4)H-h; hnsPLA2
  Boling pt:
  Melting pt:
  Solubility:Soluble in DMSO
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Meng H, Liu Y, Zhai Y, Lai L. Optimization of 5-hydroxytryptamines as dual function inhibitors targeting phospholipase A2 and leukotriene A4 hydrolase. Eur J Med Chem. 2013 Jan;59:160-7

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting