• Product NameCID-25014542
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityCID-25014542 is novel inhibitor of Raf kinases.
• Target NameRaf inhibitor
• CAS No. 220904-99-4
• Calculated MW 429.49
• Formulation C15H8Br2ClNO2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:C1=CC2=C(C=C1Cl)/C(=C/C3=CC(=C(C(=C3)Br)O)Br)/C(=O)N2
  Pathways:MAPK
  Receptor:Raf
  Boling pt:
  Melting pt:
  Solubility:Soluble in DMSO
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Lulli D, Carbone ML, Pastore S. The MEK Inhibitors Trametinib and Cobimetinib Induce a Type I Interferon Response in Human Keratinocytes. Int J Mol Sci. 2017 Oct 24;18(10)

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting