• Product NameAvibactam
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityAvibactam is a covalent, reversible, β-lactamase inhibitor with IC50 values of 8, 80, and 38 nM for TEM-1, P99, and KPC-2 β-lactamases, respectively.
• Target NameAntibacterial inhibitor
• CAS No. 1192491-61-4
• Calculated MW 287.222
• Formulation C7H10N3NaO6S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:inflammation
  SMILES:C1C[C@H](N2C[C@@H]1N(C2=O)OS(=O)(=O)[O-])C(=O)N.[Na+]
  Pathways:Microbiology&virology
  Receptor:CTX-M-15; KPC-2 β-lactamases; P99 β-lactamases; TEM-1 β-lactamases
  Boling pt:
  Melting pt:
  Solubility:DMSO 57 mg/mL (198.44 mM) Water 57 mg/mL (198.44 mM) Ethanol Insoluble
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Ehmann DE, et al. Avibactam is a covalent, reversible, non-β-lactam β-lactamase inhibitor. Proc Natl Acad Sci U S A. 2012 Jul 17;109(29):11663-8.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting